G enerally, Tylenol might not show up in a standard drug test unless specifically tested. But when combined with Codeine, it might show up in your 12-panel drug test as opiates. This might happen if you are taking the medication without a prescription. Tylenol might contain less than 90 milligrams of Codeine in them, making them a schedule III drug that leads to the possibility of showing up even in a standard 5-panel drug test . This blog will help you know about Tylenol and does it show up in your 12-panel drug test. What is Tylenol? Tylenol ( Acetaminophen) is used to treat muscle pain after a heavy workout, treating fever, and headache. It is an over-the-counter medication, but it should be taken only based on the prescription. It does not lead to any side effects or allergic reactions, but it is better to consult your doctor if it occurs. When taken along with Codeine, it has the potential of driving one to dependency. Codeine is an opiate, and hence it may show ...